Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of medicinal chemistry 1998-07, Vol.41 (15), p.2786-2805
Hauptverfasser: Webber, Stephen E., Okano, Koji, Little, Thomas L., Reich, Siegfried H., Xin, Yue, Fuhrman, Shella A., Matthews, David A., Love, Robert A., Hendrickson, Thomas F., Patick, Amy K., Meador, James W., Ferre, Rose Ann, Brown, Edward L., Ford, Clifford E., Binford, Susan L., Worland, Stephen T.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 2805
container_issue 15
container_start_page 2786
container_title Journal of medicinal chemistry
container_volume 41
creator Webber, Stephen E.
Okano, Koji
Little, Thomas L.
Reich, Siegfried H.
Xin, Yue
Fuhrman, Shella A.
Matthews, David A.
Love, Robert A.
Hendrickson, Thomas F.
Patick, Amy K.
Meador, James W.
Ferre, Rose Ann
Brown, Edward L.
Ford, Clifford E.
Binford, Susan L.
Worland, Stephen T.
description
doi_str_mv 10.1021/jm980071x
format Article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1021_jm980071x</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1021_jm980071x</sourcerecordid><originalsourceid>FETCH-LOGICAL-c159t-ece9e7fc36fb6928aac83836e4b3e23f867f20b6f557e6e4a5fe2e54e5c31ab93</originalsourceid><addsrcrecordid>eNo9UMtOwzAQtBBIlMKBP_AVqQE_mhe3UkpbqRJVW86R464bV0kc2U5Fb1z5IH6ILyEViNPO7o5mRoPQLSX3lDD6sK_ShJCYvp-hHg0ZCYYJGZ6jHiGMBSxi_BJdObcnhHDKeA99baxuoPF6C3hUbqE4dmBeFzrX3liHjcKzthI1XhW6NgdtW4f5GC-t8SAcPH5_fOJncHpXD_D6WPuiw26An7QpzU5LUeLJQZSt8Np0DFFv8dhIe3S--6y9baVvLeC1KdsT42S3xBRPu1VUuu6iOOM8WC3xCppSSKig9u4aXShROrj5m3309jLZjGfB4nU6H48WgaRh6gOQkEKsJI9UHqUsEUImPOERDHMOjKskihUjeaTCMIbuKkIFDMIhhJJTkae8j-5-daU1zllQWWN1JewxoyQ79Z39981_AEWoeIo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements</title><source>ACS Publications</source><creator>Webber, Stephen E. ; Okano, Koji ; Little, Thomas L. ; Reich, Siegfried H. ; Xin, Yue ; Fuhrman, Shella A. ; Matthews, David A. ; Love, Robert A. ; Hendrickson, Thomas F. ; Patick, Amy K. ; Meador, James W. ; Ferre, Rose Ann ; Brown, Edward L. ; Ford, Clifford E. ; Binford, Susan L. ; Worland, Stephen T.</creator><creatorcontrib>Webber, Stephen E. ; Okano, Koji ; Little, Thomas L. ; Reich, Siegfried H. ; Xin, Yue ; Fuhrman, Shella A. ; Matthews, David A. ; Love, Robert A. ; Hendrickson, Thomas F. ; Patick, Amy K. ; Meador, James W. ; Ferre, Rose Ann ; Brown, Edward L. ; Ford, Clifford E. ; Binford, Susan L. ; Worland, Stephen T.</creatorcontrib><identifier>ISSN: 0022-2623</identifier><identifier>EISSN: 1520-4804</identifier><identifier>DOI: 10.1021/jm980071x</identifier><language>eng</language><ispartof>Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2786-2805</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c159t-ece9e7fc36fb6928aac83836e4b3e23f867f20b6f557e6e4a5fe2e54e5c31ab93</citedby><cites>FETCH-LOGICAL-c159t-ece9e7fc36fb6928aac83836e4b3e23f867f20b6f557e6e4a5fe2e54e5c31ab93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,2752,27905,27906</link.rule.ids></links><search><creatorcontrib>Webber, Stephen E.</creatorcontrib><creatorcontrib>Okano, Koji</creatorcontrib><creatorcontrib>Little, Thomas L.</creatorcontrib><creatorcontrib>Reich, Siegfried H.</creatorcontrib><creatorcontrib>Xin, Yue</creatorcontrib><creatorcontrib>Fuhrman, Shella A.</creatorcontrib><creatorcontrib>Matthews, David A.</creatorcontrib><creatorcontrib>Love, Robert A.</creatorcontrib><creatorcontrib>Hendrickson, Thomas F.</creatorcontrib><creatorcontrib>Patick, Amy K.</creatorcontrib><creatorcontrib>Meador, James W.</creatorcontrib><creatorcontrib>Ferre, Rose Ann</creatorcontrib><creatorcontrib>Brown, Edward L.</creatorcontrib><creatorcontrib>Ford, Clifford E.</creatorcontrib><creatorcontrib>Binford, Susan L.</creatorcontrib><creatorcontrib>Worland, Stephen T.</creatorcontrib><title>Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements</title><title>Journal of medicinal chemistry</title><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><recordid>eNo9UMtOwzAQtBBIlMKBP_AVqQE_mhe3UkpbqRJVW86R464bV0kc2U5Fb1z5IH6ILyEViNPO7o5mRoPQLSX3lDD6sK_ShJCYvp-hHg0ZCYYJGZ6jHiGMBSxi_BJdObcnhHDKeA99baxuoPF6C3hUbqE4dmBeFzrX3liHjcKzthI1XhW6NgdtW4f5GC-t8SAcPH5_fOJncHpXD_D6WPuiw26An7QpzU5LUeLJQZSt8Np0DFFv8dhIe3S--6y9baVvLeC1KdsT42S3xBRPu1VUuu6iOOM8WC3xCppSSKig9u4aXShROrj5m3309jLZjGfB4nU6H48WgaRh6gOQkEKsJI9UHqUsEUImPOERDHMOjKskihUjeaTCMIbuKkIFDMIhhJJTkae8j-5-daU1zllQWWN1JewxoyQ79Z39981_AEWoeIo</recordid><startdate>19980716</startdate><enddate>19980716</enddate><creator>Webber, Stephen E.</creator><creator>Okano, Koji</creator><creator>Little, Thomas L.</creator><creator>Reich, Siegfried H.</creator><creator>Xin, Yue</creator><creator>Fuhrman, Shella A.</creator><creator>Matthews, David A.</creator><creator>Love, Robert A.</creator><creator>Hendrickson, Thomas F.</creator><creator>Patick, Amy K.</creator><creator>Meador, James W.</creator><creator>Ferre, Rose Ann</creator><creator>Brown, Edward L.</creator><creator>Ford, Clifford E.</creator><creator>Binford, Susan L.</creator><creator>Worland, Stephen T.</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19980716</creationdate><title>Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements</title><author>Webber, Stephen E. ; Okano, Koji ; Little, Thomas L. ; Reich, Siegfried H. ; Xin, Yue ; Fuhrman, Shella A. ; Matthews, David A. ; Love, Robert A. ; Hendrickson, Thomas F. ; Patick, Amy K. ; Meador, James W. ; Ferre, Rose Ann ; Brown, Edward L. ; Ford, Clifford E. ; Binford, Susan L. ; Worland, Stephen T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c159t-ece9e7fc36fb6928aac83836e4b3e23f867f20b6f557e6e4a5fe2e54e5c31ab93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Webber, Stephen E.</creatorcontrib><creatorcontrib>Okano, Koji</creatorcontrib><creatorcontrib>Little, Thomas L.</creatorcontrib><creatorcontrib>Reich, Siegfried H.</creatorcontrib><creatorcontrib>Xin, Yue</creatorcontrib><creatorcontrib>Fuhrman, Shella A.</creatorcontrib><creatorcontrib>Matthews, David A.</creatorcontrib><creatorcontrib>Love, Robert A.</creatorcontrib><creatorcontrib>Hendrickson, Thomas F.</creatorcontrib><creatorcontrib>Patick, Amy K.</creatorcontrib><creatorcontrib>Meador, James W.</creatorcontrib><creatorcontrib>Ferre, Rose Ann</creatorcontrib><creatorcontrib>Brown, Edward L.</creatorcontrib><creatorcontrib>Ford, Clifford E.</creatorcontrib><creatorcontrib>Binford, Susan L.</creatorcontrib><creatorcontrib>Worland, Stephen T.</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Webber, Stephen E.</au><au>Okano, Koji</au><au>Little, Thomas L.</au><au>Reich, Siegfried H.</au><au>Xin, Yue</au><au>Fuhrman, Shella A.</au><au>Matthews, David A.</au><au>Love, Robert A.</au><au>Hendrickson, Thomas F.</au><au>Patick, Amy K.</au><au>Meador, James W.</au><au>Ferre, Rose Ann</au><au>Brown, Edward L.</au><au>Ford, Clifford E.</au><au>Binford, Susan L.</au><au>Worland, Stephen T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements</atitle><jtitle>Journal of medicinal chemistry</jtitle><date>1998-07-16</date><risdate>1998</risdate><volume>41</volume><issue>15</issue><spage>2786</spage><epage>2805</epage><pages>2786-2805</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><doi>10.1021/jm980071x</doi><tpages>20</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-2623
ispartof Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2786-2805
issn 0022-2623
1520-4804
language eng
recordid cdi_crossref_primary_10_1021_jm980071x
source ACS Publications
title Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P 1 Glutamine Isosteric Replacements
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T17%3A53%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Tripeptide%20Aldehyde%20Inhibitors%20of%20Human%20Rhinovirus%203C%20Protease:%E2%80%89%20Design,%20Synthesis,%20Biological%20Evaluation,%20and%20Cocrystal%20Structure%20Solution%20of%20P%201%20Glutamine%20Isosteric%20Replacements&rft.jtitle=Journal%20of%20medicinal%20chemistry&rft.au=Webber,%20Stephen%20E.&rft.date=1998-07-16&rft.volume=41&rft.issue=15&rft.spage=2786&rft.epage=2805&rft.pages=2786-2805&rft.issn=0022-2623&rft.eissn=1520-4804&rft_id=info:doi/10.1021/jm980071x&rft_dat=%3Ccrossref%3E10_1021_jm980071x%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true