The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses
Gespeichert in:
Veröffentlicht in: | Journal of medicinal chemistry 1996-01, Vol.39 (22), p.4460-4470 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 4470 |
---|---|
container_issue | 22 |
container_start_page | 4460 |
container_title | Journal of medicinal chemistry |
container_volume | 39 |
creator | Inoue, Atsushi Kawai, Takatoshi Wakita, Misako Iimura, Youichi Sugimoto, Hachiro Kawakami, Yoshiyuki |
description | |
doi_str_mv | 10.1021/jm950596e |
format | Article |
fullrecord | <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1021_jm950596e</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1021_jm950596e</sourcerecordid><originalsourceid>FETCH-LOGICAL-c74e-29fd5381e9745286527ba6bbd3176df4d174cb65cdf01d0627de5f43f317e3703</originalsourceid><addsrcrecordid>eNo9kU9qGzEYxUVpoW7aRW-gpQ1Rqz-jGXs5dZM6ECgk3oVgZqRvOgqyNEhyqG7QdW-SK-QoOUcWHWdKVh-89_jxPh5Cnxn9wihnX-_2K0nlqoQ3aMYkp6RY0uItmlHKOeElF-_RhxjvKKWCcTFDz9se8LXZH2yTQONvxmnjfmHf4fnjw4LwU0G-mz7r4Ik8LYk2e0i9_50JJzc3jMyHHly2RzHbBSkIHswAwYyQbG8n-ZYwvMFkJIMjjHgHeHMEqt76MQl4fsYppwvcOI2vYCpy4XrTmuRDxMnj8wDwYtcqT36tIGWrem-Ng5ggNBHiS2TtQ4A4-OmR6xQOKh0CPP35W6tk7k3KuHaNzWP-I3rXNTbCp__3BG3Pz7brDbn8-eNiXV8SVRVA-KrTUiwZrKpC8mUpedU2ZdtqwapSd4VmVaHaUirdUaZpySsNsitEN_ogKipO0GLCquBjDNDthmD2Tcg7RnfH1Xavq4l_j8SOqg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses</title><source>ACS Publications</source><creator>Inoue, Atsushi ; Kawai, Takatoshi ; Wakita, Misako ; Iimura, Youichi ; Sugimoto, Hachiro ; Kawakami, Yoshiyuki</creator><creatorcontrib>Inoue, Atsushi ; Kawai, Takatoshi ; Wakita, Misako ; Iimura, Youichi ; Sugimoto, Hachiro ; Kawakami, Yoshiyuki</creatorcontrib><identifier>ISSN: 0022-2623</identifier><identifier>EISSN: 1520-4804</identifier><identifier>DOI: 10.1021/jm950596e</identifier><language>eng</language><ispartof>Journal of medicinal chemistry, 1996-01, Vol.39 (22), p.4460-4470</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c74e-29fd5381e9745286527ba6bbd3176df4d174cb65cdf01d0627de5f43f317e3703</citedby><cites>FETCH-LOGICAL-c74e-29fd5381e9745286527ba6bbd3176df4d174cb65cdf01d0627de5f43f317e3703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2763,27922,27923</link.rule.ids></links><search><creatorcontrib>Inoue, Atsushi</creatorcontrib><creatorcontrib>Kawai, Takatoshi</creatorcontrib><creatorcontrib>Wakita, Misako</creatorcontrib><creatorcontrib>Iimura, Youichi</creatorcontrib><creatorcontrib>Sugimoto, Hachiro</creatorcontrib><creatorcontrib>Kawakami, Yoshiyuki</creatorcontrib><title>The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses</title><title>Journal of medicinal chemistry</title><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><recordid>eNo9kU9qGzEYxUVpoW7aRW-gpQ1Rqz-jGXs5dZM6ECgk3oVgZqRvOgqyNEhyqG7QdW-SK-QoOUcWHWdKVh-89_jxPh5Cnxn9wihnX-_2K0nlqoQ3aMYkp6RY0uItmlHKOeElF-_RhxjvKKWCcTFDz9se8LXZH2yTQONvxmnjfmHf4fnjw4LwU0G-mz7r4Ik8LYk2e0i9_50JJzc3jMyHHly2RzHbBSkIHswAwYyQbG8n-ZYwvMFkJIMjjHgHeHMEqt76MQl4fsYppwvcOI2vYCpy4XrTmuRDxMnj8wDwYtcqT36tIGWrem-Ng5ggNBHiS2TtQ4A4-OmR6xQOKh0CPP35W6tk7k3KuHaNzWP-I3rXNTbCp__3BG3Pz7brDbn8-eNiXV8SVRVA-KrTUiwZrKpC8mUpedU2ZdtqwapSd4VmVaHaUirdUaZpySsNsitEN_ogKipO0GLCquBjDNDthmD2Tcg7RnfH1Xavq4l_j8SOqg</recordid><startdate>19960101</startdate><enddate>19960101</enddate><creator>Inoue, Atsushi</creator><creator>Kawai, Takatoshi</creator><creator>Wakita, Misako</creator><creator>Iimura, Youichi</creator><creator>Sugimoto, Hachiro</creator><creator>Kawakami, Yoshiyuki</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19960101</creationdate><title>The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses</title><author>Inoue, Atsushi ; Kawai, Takatoshi ; Wakita, Misako ; Iimura, Youichi ; Sugimoto, Hachiro ; Kawakami, Yoshiyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c74e-29fd5381e9745286527ba6bbd3176df4d174cb65cdf01d0627de5f43f317e3703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Inoue, Atsushi</creatorcontrib><creatorcontrib>Kawai, Takatoshi</creatorcontrib><creatorcontrib>Wakita, Misako</creatorcontrib><creatorcontrib>Iimura, Youichi</creatorcontrib><creatorcontrib>Sugimoto, Hachiro</creatorcontrib><creatorcontrib>Kawakami, Yoshiyuki</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of medicinal chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Inoue, Atsushi</au><au>Kawai, Takatoshi</au><au>Wakita, Misako</au><au>Iimura, Youichi</au><au>Sugimoto, Hachiro</au><au>Kawakami, Yoshiyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses</atitle><jtitle>Journal of medicinal chemistry</jtitle><date>1996-01-01</date><risdate>1996</risdate><volume>39</volume><issue>22</issue><spage>4460</spage><epage>4470</epage><pages>4460-4470</pages><issn>0022-2623</issn><eissn>1520-4804</eissn><doi>10.1021/jm950596e</doi><tpages>11</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0022-2623 |
ispartof | Journal of medicinal chemistry, 1996-01, Vol.39 (22), p.4460-4470 |
issn | 0022-2623 1520-4804 |
language | eng |
recordid | cdi_crossref_primary_10_1021_jm950596e |
source | ACS Publications |
title | The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T17%3A55%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Simulated%20Binding%20of%20(%C2%B1)-2,3-Dihydro-5,6-dimethoxy-2-%5B%5B1-(phenylmethyl)-4-%20piperidinyl%5Dmethyl%5D-1%20H%20-inden-1-one%20Hydrochloride%20(E2020)%20and%20Related%20Inhibitors%20to%20Free%20and%20Acylated%20Acetylcholinesterases%20and%20Corresponding%20Structure%E2%88%92Activity%20Analyses&rft.jtitle=Journal%20of%20medicinal%20chemistry&rft.au=Inoue,%20Atsushi&rft.date=1996-01-01&rft.volume=39&rft.issue=22&rft.spage=4460&rft.epage=4470&rft.pages=4460-4470&rft.issn=0022-2623&rft.eissn=1520-4804&rft_id=info:doi/10.1021/jm950596e&rft_dat=%3Ccrossref%3E10_1021_jm950596e%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |