Identification, Synthesis, and Biological Evaluation of 6‑[(6R)‑2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5‑a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)‑one (AS1940477), a Potent p38 MAP Kinase Inhibitor

Identification, Synthesis, and Biological Evaluation of 6‑[(6R)‑2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5‑a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)‑one (AS1940477), a Potent p38 MAP Kinase Inhibitor

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Veröffentlicht in:Journal of medicinal chemistry 2014-08, Vol.57 (16), p.7143-7143
Hauptverfasser: Asano, Toru, Yamazaki, Hitoshi, Kasahara, Chiyoshi, Kubota, Hirokazu, Kontani, Toru, Harayama, Yu, Ohno, Kazuki, Mizuhara, Hidekazu, Yokomoto, Masaharu, Misumi, Keiji, Kinoshita, Tomohiko, Ohta, Mitsuaki, Takeuchi, Makoto
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container_end_page 7143
container_issue 16
container_start_page 7143
container_title Journal of medicinal chemistry
container_volume 57
creator Asano, Toru
Yamazaki, Hitoshi
Kasahara, Chiyoshi
Kubota, Hirokazu
Kontani, Toru
Harayama, Yu
Ohno, Kazuki
Mizuhara, Hidekazu
Yokomoto, Masaharu
Misumi, Keiji
Kinoshita, Tomohiko
Ohta, Mitsuaki
Takeuchi, Makoto
description
doi_str_mv 10.1021/jm501222p
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title Identification, Synthesis, and Biological Evaluation of 6‑[(6R)‑2-(4-Fluorophenyl)-6-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5‑a]pyrimidin-3-yl]-2-(2-methylphenyl)pyridazin-3(2H)‑one (AS1940477), a Potent p38 MAP Kinase Inhibitor
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