Discovery of a Rapidly Metabolized, Long-Acting β 2 Adrenergic Receptor Agonist with a Short Onset Time Incorporating a Sulfone Group Suitable for Once-Daily Dosing

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Veröffentlicht in:Journal of medicinal chemistry 2014-01, Vol.57 (1), p.159-170
Hauptverfasser: Procopiou, Panayiotis A., Barrett, Victoria J., Biggadike, Keith, Butchers, Peter R., Craven, Andrew, Ford, Alison J., Guntrip, Stephen B., Holmes, Duncan S., Hughes, Sara C., Jones, Anne E., Looker, Brian E., Mutch, Peter J., Ruston, Mark, Needham, Deborah, Smith, Claire E.
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container_end_page 170
container_issue 1
container_start_page 159
container_title Journal of medicinal chemistry
container_volume 57
creator Procopiou, Panayiotis A.
Barrett, Victoria J.
Biggadike, Keith
Butchers, Peter R.
Craven, Andrew
Ford, Alison J.
Guntrip, Stephen B.
Holmes, Duncan S.
Hughes, Sara C.
Jones, Anne E.
Looker, Brian E.
Mutch, Peter J.
Ruston, Mark
Needham, Deborah
Smith, Claire E.
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doi_str_mv 10.1021/jm401532g
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title Discovery of a Rapidly Metabolized, Long-Acting β 2 Adrenergic Receptor Agonist with a Short Onset Time Incorporating a Sulfone Group Suitable for Once-Daily Dosing
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