Investigation of 5-Nitrofuran Derivatives: Synthesis, Antibacterial Activity, and Quantitative Structure−Activity Relationships

Three sets of antibacterial nitrofuran derivatives [set I, 5-R-substituted (Z)-2-(5-nitrofuran-2-ylmethylene)-3(2H)-benzofuranones (R = OCH3, H, CH3, C2H5, nC3H7, Cl, Br, CN, and NO2) and their 2-hydroxyphenyl and 2-acetoxyphenyl analogues; set II, 5-R-substituted (E)-1-(2-hydroxyphenyl)-3-(5-nitrof...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 2001-10, Vol.44 (22), p.3673-3681
Hauptverfasser:	Pires, José Ricardo, Saito, Cristina, Gomes, Suely L, Giesbrecht, Astréa M, Amaral, Antonia T-do
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Caulobacter crescentus - drug effects Chromatography, High Pressure Liquid Inhibitory Concentration 50 Medical sciences Microbial Sensitivity Tests Nitrofurans - chemical synthesis Nitrofurans - chemistry Nitrofurans - pharmacology Oxidation-Reduction Pharmacology. Drug treatments Quantitative Structure-Activity Relationship Staphylococcus aureus - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!