Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

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Veröffentlicht in:Journal of medicinal chemistry 1989-03, Vol.32 (3), p.715-720
Hauptverfasser: Hertzberg, Robert P, Caranfa, Mary Jo, Holden, Kenneth G, Jakas, Dalia R, Gallagher, Gregory, Mattern, Michael R, Mong, Shau Ming, Bartus, Joan O'Leary, Johnson, Randall K, Kingsbury, William D
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container_end_page 720
container_issue 3
container_start_page 715
container_title Journal of medicinal chemistry
container_volume 32
creator Hertzberg, Robert P
Caranfa, Mary Jo
Holden, Kenneth G
Jakas, Dalia R
Gallagher, Gregory
Mattern, Michael R
Mong, Shau Ming
Bartus, Joan O'Leary
Johnson, Randall K
Kingsbury, William D
description
doi_str_mv 10.1021/jm00123a038
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title Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity
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