Acute Toxicity of High Doses of the Glycoalkaloids, α-Solanine and α-Chaconine, in the Syrian Golden Hamster

Sprouted, stressed, or spoiled potato tubers have reportedly led to human acute intoxication, coma, and death when consumed in high amounts. These effects have been attributed to glycoalkaloids (GAs), primarily α-solanine and α-chaconine, naturally present in all potatoes. The level of GAs in potato...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2008-09, Vol.56 (18), p.8753-8760
Hauptverfasser:	Langkilde, Søren, Schrøder, Malene, Stewart, Derek, Meyer, Otto, Conner, Sean, Davies, Howard, Poulsen, Morten
Format:	Artikel
Sprache:	eng
Schlagworte:	acetyl cholinesterase Acetylcholinesterase - drug effects acute toxicity alpha-chaconine alpha-solanine animal models Animals Biological and medical sciences Butyrylcholinesterase - drug effects Cricetinae dose response Dose-Response Relationship, Drug Female Food industries Fruit and vegetable industries Fundamental and applied biological sciences. Psychology Glycoalkaloid glycoalkaloids golden hamsters hamster Intestine, Small - drug effects lethal dose Mesocricetus metabolomics potato potatoes Solanine - administration & dosage Solanine - analogs & derivatives Solanine - analysis Solanine - toxicity Toxicology in Agriculture and Food α-chaconine α-solanine
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