Inhibition of Lipopolysaccharide (LPS)-Induced Inflammatory Responses by Sargassum hemiphyllum Sulfated Polysaccharide Extract in RAW 264.7 Macrophage Cells

Sargassum hemiphyllum, a kind of brown seaweed generally found along coastlines in East Asia, has long served as a traditional Chinese medicine. S. hemiphyllum has shown an anti-inflammatory effect; however, its mechanism has not been elucidated clearly. This study explored S. hemiphyllum for its bi...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2011-03, Vol.59 (5), p.2062-2068
Hauptverfasser:	Hwang, Pai-An, Chien, Shih-Yung, Chan, Yi-Lin, Lu, Mei-Kuang, Wu, Chwen-Herng, Kong, Zwe-Ling, Wu, Chang-Jer
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-inflammatory activity Biological and medical sciences Cell Line coasts Cyclooxygenase 2 - genetics Cytokines - metabolism Food Chemistry/Biochemistry Food industries Fundamental and applied biological sciences. Psychology gene expression inflammation Inflammation - chemically induced Inflammation - prevention & control interleukin-1 Interleukin-1beta - genetics interleukin-6 lipopolysaccharides Lipopolysaccharides - antagonists & inhibitors Lipopolysaccharides - pharmacology macroalgae macrophages Macrophages - chemistry Macrophages - drug effects Macrophages - physiology messenger RNA Mice NF-kappa B - analysis nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase Type II - genetics Oriental traditional medicine Polysaccharides - pharmacology reverse transcriptase polymerase chain reaction RNA, Messenger - analysis Sargassum Sargassum - chemistry Sulfates - pharmacology tumor necrosis factor-alpha Western blotting
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