Nephrocalcinosis Formation by Soy Isoflavones in Male Rats

Isoflavones (IFs), found in the form of both aglycones and glucosides in soybean foods, induce weak estrogenic activities. Although IFs have a number of health benefits, it was previously reported that IFs cause nephrocalcinosis (NC) in the kidney of male Fischer 344 (F344) rats. The present study a...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2006-07, Vol.54 (15), p.5659-5663
Hauptverfasser:	Satoh, Takuya, Yamakoshi, Jun, Saito, Makoto, Izumi, Toru, Matsuyama, Asahi, Kikuchi, Mamoru, Yamaguchi, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences calcium chemical precipitation dosage Fermentation fermented soybean extract Food industries Fundamental and applied biological sciences. Psychology Glycine max - chemistry histopathology intestinal absorption isoflavones Isoflavones - administration & dosage Isoflavones - adverse effects kidneys Male males nephrocalcinosis Nephrocalcinosis - chemically induced oral administration Plant Extracts - chemistry Rats Rats, Inbred F344 Rats, Sprague-Dawley soybeans Species Specificity toxicity
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