Epicatechin and Catechin in Cocoa Inhibit Amyloid β Protein Induced Apoptosis

To elucidate additional health benefits of cocoa phytochemicals on the neurotoxicity induced by amyloid β protein (Aβ), PC12 cells were treated with toxic peptide (Aβ25 - 35) and the effects of epicatechin, catechin, and cocoa were studied using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium b...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2005-03, Vol.53 (5), p.1445-1448
Hauptverfasser:	Heo, Ho Jin, Lee, Chang Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer disease amyloid beta protein Amyloid beta-Peptides - pharmacology animal proteins Animals apoptosis Apoptosis - drug effects Biological and medical sciences brain Cacao - chemistry catechin Catechin - pharmacology Cell Membrane - drug effects cocoa (beverage) epicatechin General pharmacology Medical sciences medicinal properties Neurodegenerative Diseases - prevention & control Neurons - drug effects Neurons - ultrastructure neurotoxicity PC12 Cells Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Rats
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