Antioxidative and Antiinflammatory Compounds from Tropical Gingers: Isolation, Structure Determination, and Activities of Cassumunins A, B, and C, New Complex Curcuminoids from Zingiber cassumunar
Assay-guided isolation gave three new compounds, cassumunins A, B, and C, having both antioxidant and antiinflammatory activities, from the rhizomes of a tropical ginger, Zingiber cassumunar. Antioxidant activity and antiinflammatory activity were measured using a thiocyanate method and a 12-O-tetra...
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| Veröffentlicht in: | Journal of agricultural and food chemistry 1994-09, Vol.42 (9), p.1850-1856 |
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| container_title | Journal of agricultural and food chemistry |
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| creator | Masuda, Toshiya Jitoe, Akiko |
| description | Assay-guided isolation gave three new compounds, cassumunins A, B, and C, having both antioxidant and antiinflammatory activities, from the rhizomes of a tropical ginger, Zingiber cassumunar. Antioxidant activity and antiinflammatory activity were measured using a thiocyanate method and a 12-O-tetradecanoylphorbol 13-acetate-induced method on mouse ear, respectively. The antioxidant activity of cassumunins A-C is stronger than that of curcumin, and their antiinflammatory activity is also stronger than that of curcumin. Spectroscopic analysis of cassumunins A-C revealed them to be a new type of complex curcumin. Antioxidant and antiinflammatory activities of cassumunins suggested that the substituted group at the 5'-position of curcumin increased both activities |
| doi_str_mv | 10.1021/jf00045a004 |
| format | Article |
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Antioxidant activity and antiinflammatory activity were measured using a thiocyanate method and a 12-O-tetradecanoylphorbol 13-acetate-induced method on mouse ear, respectively. The antioxidant activity of cassumunins A-C is stronger than that of curcumin, and their antiinflammatory activity is also stronger than that of curcumin. Spectroscopic analysis of cassumunins A-C revealed them to be a new type of complex curcumin. Antioxidant and antiinflammatory activities of cassumunins suggested that the substituted group at the 5'-position of curcumin increased both activities</description><identifier>ISSN: 0021-8561</identifier><identifier>EISSN: 1520-5118</identifier><identifier>DOI: 10.1021/jf00045a004</identifier><identifier>CODEN: JAFCAU</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Biological and medical sciences ; Food additives ; Food industries ; Fundamental and applied biological sciences. 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Agric. Food Chem</addtitle><description>Assay-guided isolation gave three new compounds, cassumunins A, B, and C, having both antioxidant and antiinflammatory activities, from the rhizomes of a tropical ginger, Zingiber cassumunar. Antioxidant activity and antiinflammatory activity were measured using a thiocyanate method and a 12-O-tetradecanoylphorbol 13-acetate-induced method on mouse ear, respectively. The antioxidant activity of cassumunins A-C is stronger than that of curcumin, and their antiinflammatory activity is also stronger than that of curcumin. Spectroscopic analysis of cassumunins A-C revealed them to be a new type of complex curcumin. Antioxidant and antiinflammatory activities of cassumunins suggested that the substituted group at the 5'-position of curcumin increased both activities</description><subject>Biological and medical sciences</subject><subject>Food additives</subject><subject>Food industries</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>MEDICAMENT TRADITIONNEL</subject><subject>MEDICAMENTOS TRADICIONALES</subject><subject>PROPIEDADES MEDICINALES</subject><subject>PROPRIETE PHARMACOLOGIQUE</subject><subject>RHIZOME</subject><subject>RIZOMAS</subject><subject>ZINGIBER</subject><issn>0021-8561</issn><issn>1520-5118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><recordid>eNptkc1u1DAUhS0EEkNhxY6VF0gsmICdxPlhNw10KK0AaaZCYmPdONeVh8Qe2QlM348Hw22GigUbW_L5zjnWvYQ85-wNZyl_u9OMsVxAPB6QBRcpSwTn1UOyYFFOKlHwx-RJCLuIVaJkC_J7ZUfjDqaD0fxECrajty_G6h6GAUbnb2jjhr2bbBeo9m6gW-_2RkFP18Zeow_v6HlwffQ7u6Sb0U9qnDzS9ziiH4w9CnfJKpaY0WCgTtMGQpiGyRob6GpJT2emWdLP-Ouus8cDbSavppjizN_677HVtOipOvrBPyWPNPQBnx3vE3J19mHbfEwuv6zPm9VlAlmWjonWZa1YnnKhoECsc1YgTzVAkWZVUXegW4ZlWVZdznWrdJcitshqqNqW6y7LTsjrOVd5F4JHLffeDOBvJGfydgHynwVE-uVM7yHEcWkPVplwb8nyNMsEj1gyYyaMeLiXwf-QRZmVQm6_buS39QW7YOUneRb5FzOvwUm49jHyalMXjOe1iOKrWQQV5M5N3sZ5_Pd3fwDnO64q</recordid><startdate>19940901</startdate><enddate>19940901</enddate><creator>Masuda, Toshiya</creator><creator>Jitoe, Akiko</creator><general>American Chemical Society</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19940901</creationdate><title>Antioxidative and Antiinflammatory Compounds from Tropical Gingers: Isolation, Structure Determination, and Activities of Cassumunins A, B, and C, New Complex Curcuminoids from Zingiber cassumunar</title><author>Masuda, Toshiya ; Jitoe, Akiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a332t-ff79c04215ca6ee9406e12faa623869dafb0e7778d41fbcfd2eebe09a8bb1fd33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Biological and medical sciences</topic><topic>Food additives</topic><topic>Food industries</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>MEDICAMENT TRADITIONNEL</topic><topic>MEDICAMENTOS TRADICIONALES</topic><topic>PROPIEDADES MEDICINALES</topic><topic>PROPRIETE PHARMACOLOGIQUE</topic><topic>RHIZOME</topic><topic>RIZOMAS</topic><topic>ZINGIBER</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Masuda, Toshiya</creatorcontrib><creatorcontrib>Jitoe, Akiko</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Masuda, Toshiya</au><au>Jitoe, Akiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidative and Antiinflammatory Compounds from Tropical Gingers: Isolation, Structure Determination, and Activities of Cassumunins A, B, and C, New Complex Curcuminoids from Zingiber cassumunar</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>1994-09-01</date><risdate>1994</risdate><volume>42</volume><issue>9</issue><spage>1850</spage><epage>1856</epage><pages>1850-1856</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><coden>JAFCAU</coden><abstract>Assay-guided isolation gave three new compounds, cassumunins A, B, and C, having both antioxidant and antiinflammatory activities, from the rhizomes of a tropical ginger, Zingiber cassumunar. Antioxidant activity and antiinflammatory activity were measured using a thiocyanate method and a 12-O-tetradecanoylphorbol 13-acetate-induced method on mouse ear, respectively. The antioxidant activity of cassumunins A-C is stronger than that of curcumin, and their antiinflammatory activity is also stronger than that of curcumin. Spectroscopic analysis of cassumunins A-C revealed them to be a new type of complex curcumin. Antioxidant and antiinflammatory activities of cassumunins suggested that the substituted group at the 5'-position of curcumin increased both activities</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><doi>10.1021/jf00045a004</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-8561 |
| ispartof | Journal of agricultural and food chemistry, 1994-09, Vol.42 (9), p.1850-1856 |
| issn | 0021-8561 1520-5118 |
| language | eng |
| recordid | cdi_crossref_primary_10_1021_jf00045a004 |
| source | ACS Publications |
| subjects | Biological and medical sciences Food additives Food industries Fundamental and applied biological sciences. Psychology General aspects MEDICAMENT TRADITIONNEL MEDICAMENTOS TRADICIONALES PROPIEDADES MEDICINALES PROPRIETE PHARMACOLOGIQUE RHIZOME RIZOMAS ZINGIBER |
| title | Antioxidative and Antiinflammatory Compounds from Tropical Gingers: Isolation, Structure Determination, and Activities of Cassumunins A, B, and C, New Complex Curcuminoids from Zingiber cassumunar |
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