Kinetic Basis for the Design of Azobenzene-Based Photoswitchable A 2a Adenosine Receptor Ligands

Photoisomerization of ligands is a key process in the field of photopharmacology. Thus, the kinetics and efficiency of this initial photoreaction are of great importance but can be influenced by the molecular environment of the binding pocket and the resulting confinement of the reaction pathway. In...

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Veröffentlicht in:	Journal of the American Chemical Society 2024-11
Hauptverfasser:	Saßmannshausen, Torben, Glover, Hannah, Trabuco, Matilde, Neidhart, Werner, Cheng, Robert, Hennig, Michael, Slavov, Chavdar, Standfuss, Jörg, Wachtveitl, Josef
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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