Pd II -Catalyzed Site-selective β- and γ-C(sp 3 )-H Arylation of Primary Aldehydes Controlled by Transient Directing Groups

Pd(II)-catalyzed site-selective β- and γ-C(sp )-H arylation of primary aldehydes is developed by rational design of L,X-type transient directing groups (TDG). External 2-pyridone ligands are identified to be crucial for the observed reactivity. By minimizing the loading of acid additives, the ligand...

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Veröffentlicht in:	Journal of the American Chemical Society 2022-03, Vol.144 (11), p.4727-4733
Hauptverfasser:	Li, Yi-Hao, Ouyang, Yuxin, Chekshin, Nikita, Yu, Jin-Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Catalysis Ligands Palladium Pyridones
Online-Zugang:	Volltext
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