Enantioselective Total Synthesis of (−)-Taxol

Enantioselective total synthesis of taxol has been accomplished. Coupling reaction of the optically pure A-ring hydroxy aldehyde with the aromatic C-ring fragment followed by Lewis acid mediated eight-membered B-ring cyclization gave the desired ABC endo-tricarbocycle. The C-ring moiety of this prod...

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Veröffentlicht in:	Journal of the American Chemical Society 2000-04, Vol.122 (16), p.3811-3820
Hauptverfasser:	Kusama, Hiroyuki, Hara, Ryoma, Kawahara, Shigeru, Nishimori, Toshiyuki, Kashima, Hajime, Nakamura, Nobuhito, Morihira, Koichiro, Kuwajima, Isao
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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