Recognition of a Single Guanine Bulge by 2-Acylamino-1,8-naphthyridine
2-Acylamino-1,8-naphthyridine (1), which possesses hydrogen bonding groups fully complementary to guanine (G), selectively binds to a single G bulge of duplex DNA. The melting temperature (T m) of the duplex containing a G bulge was increased by the presence of 1, whereas no increase of T m was obse...
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Veröffentlicht in: | Journal of the American Chemical Society 2000-03, Vol.122 (10), p.2172-2177 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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