Modulation of Esterase and Amidase Activity of Subtilisin Bacillus l entus by Chemical Modification of Cysteine Mutants

For synthetic applications of proteases, such as for peptide coupling, a combination of high esterase and low amidase activities is required. While achieving such specificity has been a long-standing goal, the decreases in amidase activity achieved to date have often also been accompanied by decreas...

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Veröffentlicht in:	Journal of the American Chemical Society 1999-06, Vol.121 (21), p.4977-4981
Hauptverfasser:	Plettner, Erika, DeSantis, Grace, Stabile, Michele R, Jones, J. Bryan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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