Synthesis of a Glycopeptide Containing Oligosaccharides: Chemoenzymatic Synthesis of Eel Calcitonin Analogues Having Natural N-Linked Oligosaccharides

We describe a novel chemoenzymatic synthesis of eel calcitonin (eCT) glycopeptide analogues having natural N-linked oligosaccharides, such as a disialo biantennary complex-type [(NeuAc-Gal-GlcNAc-Man)2-Man-GlcNAc2], an asialo complex-type [(Gal-GlcNAc-Man)2-Man-GlcNAc2], and a high-mannose type [Man...

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Veröffentlicht in:Journal of the American Chemical Society 1999-01, Vol.121 (2), p.284-290
Hauptverfasser: Mizuno, Mamoru, Haneda, Katsuji, Iguchi, Reiko, Muramoto, Ikuyo, Kawakami, Toru, Aimoto, Saburo, Yamamoto, Kenji, Inazu, Toshiyuki
Format: Artikel
Sprache:eng
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