Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K
Gespeichert in:
| Veröffentlicht in: | Journal of the American Chemical Society 1998-09, Vol.120 (35), p.9114-9115 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 9115 |
|---|---|
| container_issue | 35 |
| container_start_page | 9114 |
| container_title | Journal of the American Chemical Society |
| container_volume | 120 |
| creator | DesJarlais, Renee L Yamashita, Dennis S Oh, Hye-Ja Uzinskas, Irene N Erhard, Karl F Allen, Andrew C Haltiwanger, R. Curtis Zhao, Baoguang Smith, Ward W Abdel-Meguid, Sherin S D'Alessio, Karla Janson, Cheryl A McQueney, Michael S Tomaszek, Thaddeus A Levy, Mark A Veber, Daniel F |
| description | |
| doi_str_mv | 10.1021/ja981171v |
| format | Article |
| fullrecord | <record><control><sourceid>istex_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1021_ja981171v</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_TPS_89CFG70G_G</sourcerecordid><originalsourceid>FETCH-LOGICAL-a295t-bc33ee1ed8cd663f06cc25911efb619de414d9c3d5b73cd8e0c1dd7f0b8830163</originalsourceid><addsrcrecordid>eNpt0EtLAzEQB_AgCtbHwW-QiwcP0cym-zrKqrVYH9AK3kI2mW1T101JUrEXP7urFU-eZgZ-zDB_Qk6AnwNP4GKpygIgh_cdMoA04SyFJNslA855wvIiE_vkIIRlPw6TAgbk8zkgdQ19YV5taOWY9psQVUun0a91XHsMVHWG3rsW9bpVvu8Mtrab05mjVxjsvKNPLmIXf9wUexftO9IH17EVrqI1SMfdwtY2Oh--b1UqLnAVbEfvjsheo9qAx7_1kDzfXM-qWzZ5HI2rywlTSZlGVmshEAFNoU2WiYZnWidpCYBNnUFpcAhDU2ph0joX2hTINRiTN7wuCsEhE4fkbLtXexeCx0auvH1TfiOBy-_g5F9wvWVba0PEjz-o_KvMcpGncvY0lUVZ3YxyPpKj3p9uvdJBLt3ad_0n_-z9AhhhfTc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K</title><source>ACS Publications</source><creator>DesJarlais, Renee L ; Yamashita, Dennis S ; Oh, Hye-Ja ; Uzinskas, Irene N ; Erhard, Karl F ; Allen, Andrew C ; Haltiwanger, R. Curtis ; Zhao, Baoguang ; Smith, Ward W ; Abdel-Meguid, Sherin S ; D'Alessio, Karla ; Janson, Cheryl A ; McQueney, Michael S ; Tomaszek, Thaddeus A ; Levy, Mark A ; Veber, Daniel F</creator><creatorcontrib>DesJarlais, Renee L ; Yamashita, Dennis S ; Oh, Hye-Ja ; Uzinskas, Irene N ; Erhard, Karl F ; Allen, Andrew C ; Haltiwanger, R. Curtis ; Zhao, Baoguang ; Smith, Ward W ; Abdel-Meguid, Sherin S ; D'Alessio, Karla ; Janson, Cheryl A ; McQueney, Michael S ; Tomaszek, Thaddeus A ; Levy, Mark A ; Veber, Daniel F</creatorcontrib><identifier>ISSN: 0002-7863</identifier><identifier>EISSN: 1520-5126</identifier><identifier>DOI: 10.1021/ja981171v</identifier><language>eng</language><publisher>American Chemical Society</publisher><ispartof>Journal of the American Chemical Society, 1998-09, Vol.120 (35), p.9114-9115</ispartof><rights>Copyright © 1998 American Chemical Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a295t-bc33ee1ed8cd663f06cc25911efb619de414d9c3d5b73cd8e0c1dd7f0b8830163</citedby><cites>FETCH-LOGICAL-a295t-bc33ee1ed8cd663f06cc25911efb619de414d9c3d5b73cd8e0c1dd7f0b8830163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/ja981171v$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/ja981171v$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2752,27053,27901,27902,56713,56763</link.rule.ids></links><search><creatorcontrib>DesJarlais, Renee L</creatorcontrib><creatorcontrib>Yamashita, Dennis S</creatorcontrib><creatorcontrib>Oh, Hye-Ja</creatorcontrib><creatorcontrib>Uzinskas, Irene N</creatorcontrib><creatorcontrib>Erhard, Karl F</creatorcontrib><creatorcontrib>Allen, Andrew C</creatorcontrib><creatorcontrib>Haltiwanger, R. Curtis</creatorcontrib><creatorcontrib>Zhao, Baoguang</creatorcontrib><creatorcontrib>Smith, Ward W</creatorcontrib><creatorcontrib>Abdel-Meguid, Sherin S</creatorcontrib><creatorcontrib>D'Alessio, Karla</creatorcontrib><creatorcontrib>Janson, Cheryl A</creatorcontrib><creatorcontrib>McQueney, Michael S</creatorcontrib><creatorcontrib>Tomaszek, Thaddeus A</creatorcontrib><creatorcontrib>Levy, Mark A</creatorcontrib><creatorcontrib>Veber, Daniel F</creatorcontrib><title>Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K</title><title>Journal of the American Chemical Society</title><addtitle>J. Am. Chem. Soc</addtitle><issn>0002-7863</issn><issn>1520-5126</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><recordid>eNpt0EtLAzEQB_AgCtbHwW-QiwcP0cym-zrKqrVYH9AK3kI2mW1T101JUrEXP7urFU-eZgZ-zDB_Qk6AnwNP4GKpygIgh_cdMoA04SyFJNslA855wvIiE_vkIIRlPw6TAgbk8zkgdQ19YV5taOWY9psQVUun0a91XHsMVHWG3rsW9bpVvu8Mtrab05mjVxjsvKNPLmIXf9wUexftO9IH17EVrqI1SMfdwtY2Oh--b1UqLnAVbEfvjsheo9qAx7_1kDzfXM-qWzZ5HI2rywlTSZlGVmshEAFNoU2WiYZnWidpCYBNnUFpcAhDU2ph0joX2hTINRiTN7wuCsEhE4fkbLtXexeCx0auvH1TfiOBy-_g5F9wvWVba0PEjz-o_KvMcpGncvY0lUVZ3YxyPpKj3p9uvdJBLt3ad_0n_-z9AhhhfTc</recordid><startdate>19980909</startdate><enddate>19980909</enddate><creator>DesJarlais, Renee L</creator><creator>Yamashita, Dennis S</creator><creator>Oh, Hye-Ja</creator><creator>Uzinskas, Irene N</creator><creator>Erhard, Karl F</creator><creator>Allen, Andrew C</creator><creator>Haltiwanger, R. Curtis</creator><creator>Zhao, Baoguang</creator><creator>Smith, Ward W</creator><creator>Abdel-Meguid, Sherin S</creator><creator>D'Alessio, Karla</creator><creator>Janson, Cheryl A</creator><creator>McQueney, Michael S</creator><creator>Tomaszek, Thaddeus A</creator><creator>Levy, Mark A</creator><creator>Veber, Daniel F</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19980909</creationdate><title>Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K</title><author>DesJarlais, Renee L ; Yamashita, Dennis S ; Oh, Hye-Ja ; Uzinskas, Irene N ; Erhard, Karl F ; Allen, Andrew C ; Haltiwanger, R. Curtis ; Zhao, Baoguang ; Smith, Ward W ; Abdel-Meguid, Sherin S ; D'Alessio, Karla ; Janson, Cheryl A ; McQueney, Michael S ; Tomaszek, Thaddeus A ; Levy, Mark A ; Veber, Daniel F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a295t-bc33ee1ed8cd663f06cc25911efb619de414d9c3d5b73cd8e0c1dd7f0b8830163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DesJarlais, Renee L</creatorcontrib><creatorcontrib>Yamashita, Dennis S</creatorcontrib><creatorcontrib>Oh, Hye-Ja</creatorcontrib><creatorcontrib>Uzinskas, Irene N</creatorcontrib><creatorcontrib>Erhard, Karl F</creatorcontrib><creatorcontrib>Allen, Andrew C</creatorcontrib><creatorcontrib>Haltiwanger, R. Curtis</creatorcontrib><creatorcontrib>Zhao, Baoguang</creatorcontrib><creatorcontrib>Smith, Ward W</creatorcontrib><creatorcontrib>Abdel-Meguid, Sherin S</creatorcontrib><creatorcontrib>D'Alessio, Karla</creatorcontrib><creatorcontrib>Janson, Cheryl A</creatorcontrib><creatorcontrib>McQueney, Michael S</creatorcontrib><creatorcontrib>Tomaszek, Thaddeus A</creatorcontrib><creatorcontrib>Levy, Mark A</creatorcontrib><creatorcontrib>Veber, Daniel F</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>Journal of the American Chemical Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DesJarlais, Renee L</au><au>Yamashita, Dennis S</au><au>Oh, Hye-Ja</au><au>Uzinskas, Irene N</au><au>Erhard, Karl F</au><au>Allen, Andrew C</au><au>Haltiwanger, R. Curtis</au><au>Zhao, Baoguang</au><au>Smith, Ward W</au><au>Abdel-Meguid, Sherin S</au><au>D'Alessio, Karla</au><au>Janson, Cheryl A</au><au>McQueney, Michael S</au><au>Tomaszek, Thaddeus A</au><au>Levy, Mark A</au><au>Veber, Daniel F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K</atitle><jtitle>Journal of the American Chemical Society</jtitle><addtitle>J. Am. Chem. Soc</addtitle><date>1998-09-09</date><risdate>1998</risdate><volume>120</volume><issue>35</issue><spage>9114</spage><epage>9115</epage><pages>9114-9115</pages><issn>0002-7863</issn><eissn>1520-5126</eissn><pub>American Chemical Society</pub><doi>10.1021/ja981171v</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-7863 |
| ispartof | Journal of the American Chemical Society, 1998-09, Vol.120 (35), p.9114-9115 |
| issn | 0002-7863 1520-5126 |
| language | eng |
| recordid | cdi_crossref_primary_10_1021_ja981171v |
| source | ACS Publications |
| title | Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T19%3A52%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-istex_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Use%20of%20X-ray%20Co-crystal%20Structures%20and%20Molecular%20Modeling%20To%20Design%20Potent%20and%20Selective%20Non-peptide%20Inhibitors%20of%20Cathepsin%20K&rft.jtitle=Journal%20of%20the%20American%20Chemical%20Society&rft.au=DesJarlais,%20Renee%20L&rft.date=1998-09-09&rft.volume=120&rft.issue=35&rft.spage=9114&rft.epage=9115&rft.pages=9114-9115&rft.issn=0002-7863&rft.eissn=1520-5126&rft_id=info:doi/10.1021/ja981171v&rft_dat=%3Cistex_cross%3Eark_67375_TPS_89CFG70G_G%3C/istex_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |