Role of α-Helix Conformation Cooperating with NH···S Hydrogen Bond in the Active Site of Cytochrome P-450 and Chloroperoxidase:  Synthesis and Properties of [MIII(OEP)(Cys-Helical Peptide)] (M = Fe and Ga)

Heme-thiolate protein model complexes, [FeIII(OEP)(Ac-LcXAF-LLLLL-ALFL-OMe)] {OEP = octhaethylporphinato, X = Leu (1) and Pro (2)}, having α-helical structure were synthesized and characterized as P-450 and CPO models. The stable ligation of cysteinyl thiolate at the axial position of model complexe...

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Veröffentlicht in:	Journal of the American Chemical Society 1998-12, Vol.120 (47), p.12264-12273
Hauptverfasser:	Ueno, Takafumi, Kousumi, Yukihide, Yoshizawa-Kumagaye, Kumiko, Nakajima, Kiichiro, Ueyama, Norikazu, Okamura, Taka-aki, Nakamura, Akira
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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