Photosensitized Oxidation of 5-Methyl-2‘-deoxycytidine by 2-Methyl-1,4-naphthoquinone: Characterization of 5-(Hydroperoxymethyl)-2‘-deoxycytidine and Stable Methyl Group Oxidation Products
5-Methylcytosine is a minor nucleobase of eukaryotic DNA which plays a central role in the regulation of gene expression. UV-A irradiation of an aerated aqueous solution of 5-methyl-2‘-deoxycytidine in the presence of menadione (MQ) as a type I photosensitizer leads to the formation of several stabl...
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| Veröffentlicht in: | Journal of the American Chemical Society 1996-11, Vol.118 (46), p.11406-11411 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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