UV Resonance Raman Ground and Excited State Studies of Amide and Peptide Isomerization Dynamics

We report the first measurements of the activation barrier for ground state trans−cis isomerization of secondary amides. We measured activation barriers of E a = 13.8 ± 0.8 kcal/mol for aqueous solutions of N-methylacetamide (NMA) and E a = 11.0 ± 0.7 kcal/mol for glycylglycine (Gly-Gly). These acti...

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Veröffentlicht in:	Journal of the American Chemical Society 1997-02, Vol.119 (5), p.1116-1120
Hauptverfasser:	Li, Pusheng, Chen, X. G, Shulin, E, Asher, Sanford A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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