Enzymatic Synthesis of Periodic DNA Nanoribbons for Intracellular pH Sensing and Gene Silencing

We report the construction of periodic DNA nanoribbons (DNRs) by a modified DNA origami method. Unlike the conventional DNA origami, the DNR scaffold is a long, single-stranded DNA of tandem repeats, originating from the rolling circular amplification (RCA). Consequently, the number of folding stapl...

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Veröffentlicht in:	Journal of the American Chemical Society 2015-03, Vol.137 (11), p.3844-3851
Hauptverfasser:	Chen, Gang, Liu, Di, He, Chunbai, Gannett, Theodore R, Lin, Wenbin, Weizmann, Yossi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques DNA - chemical synthesis Gene Silencing Hydrogen-Ion Concentration Microscopy, Atomic Force Nanostructures - chemistry Nucleic Acid Amplification Techniques Nucleic Acid Conformation
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