Total Synthesis of Brevetoxin-B

Brevetoxin-B (BTX-B), produced by the red tide organism, Gymnodium breve Davis, is the first member of marine polycyclic ethers to be structurally elucidated and one of the most potent neurotoxins. The structural feature is a trans-fused polycyclic ether ring system with 23 stereocenters. Its unique...

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Veröffentlicht in:Journal of the American Chemical Society 2004-11, Vol.126 (44), p.14374-14376
Hauptverfasser: Matsuo, Goh, Kawamura, Koji, Hori, Nobuyuki, Matsukura, Hiroko, Nakata, Tadashi
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Sprache:eng
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