Synthesis and Single-Crystal X-ray Investigation of 4-Azido-2-(triphenylphosphinimino)-3,5,6- trifluorobenzonitrile:  A Chromogenic Nitrene Precursor for Photolabeling

In continuation of earlier studies on the development of photolabeling agents, the authors report here the synthesis and single crystal X-ray structure of 4-azido-2-(triphenylphosphinimino)-3,5,6-trifluorobenzonitrile, 2, a chromogenic nitrene precursor, and the complexation of 2 with Pd(II). The fundamental coordination properties of the Pd(II) complex system can be extended to the corresponding analogues with {sup 109}Pd, a {beta}-emitting therapeutic radionuclide for use in radioimmunotherapy.