Application of Continuous Crystallization in an Integrated Continuous Pharmaceutical Pilot Plant

Real-time control using process analytical technology (PAT) tools is required for the implementation of continuous crystallization within integrated continuous manufacturing (ICM) of pharmaceuticals. However, appropriate selection of PAT tools is challenging, and the design and operation of automate...

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Veröffentlicht in:Crystal growth & design 2014-05, Vol.14 (5), p.2148-2157
Hauptverfasser: Zhang, Haitao, Lakerveld, Richard, Heider, Patrick L, Tao, Mengying, Su, Min, Testa, Christopher J, D’Antonio, Alyssa N, Barton, Paul I, Braatz, Richard D, Trout, Bernhardt L, Myerson, Allan S, Jensen, Klavs F, Evans, James M. B
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Sprache:eng
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