Functionalized Silica Nanoparticles as Additives for Polymorphic Control in Emulsion-Based Crystallization of Glycine

Emulsion-based crystallization to produce spherical crystalline agglomerates is an attractive route to control the size and morphology of active pharmaceutical ingredient (API) crystals, which in turn improves downstream processability. Here, we demonstrate the use of silica nanoparticles modified w...

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Veröffentlicht in:	Crystal growth & design 2013-06, Vol.13 (6), p.2455-2461
Hauptverfasser:	Md. Badruddoza, Abu Zayed, Toldy, Arpad I, Hatton, T. Alan, Khan, Saif A
Format:	Artikel
Sprache:	eng
Schlagworte:	Condensed matter: structure, mechanical and thermal properties Cross-disciplinary physics: materials science rheology Crystalline state (including molecular motions in solids) Crystallographic aspects of phase transformations pressure effects Equations of state, phase equilibria, and phase transitions Exact sciences and technology Materials science Nanoscale materials and structures: fabrication and characterization Other topics in nanoscale materials and structures Physics Solid-solid transitions Specific phase transitions Structure of solids and liquids crystallography Structure of specific crystalline solids
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