Improving the Poor Aqueous Solubility of Nutraceutical Compound Pterostilbene through Cocrystal Formation

Pterostilbene is a nutraceutical compound being investigated for its ability to form cocrystals with pharmaceutically acceptable coformers to improve its poor aqueous solubility. Cocrystals of a 2:1 and 1:1 stoichiometric molar ratio of pterostilbene with piperazine or glutaric acid were synthesized...

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Veröffentlicht in:	Crystal growth & design 2011-07, Vol.11 (7), p.2817-2823
Hauptverfasser:	Bethune, Sarah J, Schultheiss, Nate, Henck, Jan-Olav
Format:	Artikel
Sprache:	eng
Schlagworte:	Condensed matter: structure, mechanical and thermal properties Cross-disciplinary physics: materials science rheology Equations of state, phase equilibria, and phase transitions Exact sciences and technology Materials science Phase diagrams and microstructures developed by solidification and solid-solid phase transformations Physics Precipitation Solubility, segregation, and mixing phase separation
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