Tuning the pH Responsiveness of β-Hairpin Peptide Folding, Self-Assembly, and Hydrogel Material Formation

A design strategy to control the thermally triggered folding, self-assembly, and subsequent hydrogelation of amphiphilic β-hairpin peptides in a pH-dependent manner is presented. Point substitutions of the lysine residues of the self-assembling peptide MAX1 were made to alter the net charge of the p...

Ausführliche Beschreibung