Amphoteric Agmatine Containing Polyamidoamines as Carriers for Plasmid DNA In Vitro and In Vivo Delivery

In this paper we report on the investigation, as DNA nonviral carriers, of three samples of an amphoteric polyamidoamine bearing 4-aminobutylguanidine deriving units, AGMA5, AGMA10, and AGMA20, characterized by different molecular weights (M̅ w 5100, 10100, and 20500, respectively). All samples cond...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomacromolecules 2010-10, Vol.11 (10), p.2667-2674
Hauptverfasser:	Cavalli, Roberta, Bisazza, Agnese, Sessa, Roberto, Primo, Luca, Fenili, Fabio, Manfredi, Amedea, Ranucci, Elisabetta, Ferruti, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Agmatine - adverse effects Agmatine - analogs & derivatives Agmatine - chemical synthesis Agmatine - chemistry Applied sciences Biological and medical sciences Cell Survival - drug effects Deoxyribonucleases - chemistry DNA - administration & dosage DNA - genetics Drug Carriers - chemistry Drug Stability Exact sciences and technology Gene Transfer Techniques General pharmacology HeLa Cells Humans Medical sciences Microscopy, Electron, Transmission Molecular Weight Organic polymers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physicochemistry of polymers Plasmids - administration & dosage Plasmids - genetics Polyamines - adverse effects Polyamines - chemical synthesis Polyamines - chemistry Polymers with particular properties Preparation, kinetics, thermodynamics, mechanism and catalysts Surface Properties Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!