Modulation of Juxtamembrane Cleavage (“Shedding”) of Angiotensin-Converting Enzyme by Stalk Glycosylation: Evidence for an Alternative Shedding Protease

The role of juxtamembrane stalk glycosylation in modulating stalk cleavage and shedding of membrane proteins remains unresolved, despite reports that proteins expressed in glycosylation-deficient cells undergo accelerated proteolysis. We have constructed stalk glycosylation mutants of angiotensin-co...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 1999-08, Vol.38 (32), p.10388-10397
Hauptverfasser:	Schwager, Sylva L. U, Chubb, Anthony J, Scholle, Renate R, Brandt, Wolf F, Mentele, Reinhard, Riordan, James F, Sturrock, Edward D, Ehlers, Mario R. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Carbohydrates - analysis Cell-Free System - chemistry Cell-Free System - metabolism CHO Cells Cricetinae Glycosylation Humans Kinetics Membrane Proteins - biosynthesis Membrane Proteins - chemistry Membrane Proteins - genetics Membrane Proteins - metabolism Molecular Sequence Data Molecular Weight Mutagenesis, Site-Directed Peptide Fragments - chemistry Peptide Fragments - genetics Peptide Fragments - metabolism Peptidyl-Dipeptidase A - biosynthesis Peptidyl-Dipeptidase A - chemistry Peptidyl-Dipeptidase A - genetics Peptidyl-Dipeptidase A - metabolism Recombinant Proteins - biosynthesis Recombinant Proteins - chemistry Recombinant Proteins - metabolism Sequence Deletion Solubility
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!