Contribution of Cysteine 158, the Glycosylation Site Theonine 194, the Amino- and Carboxy-Terminal Domains of Apolipoprotein E in the Binding to Amyloid Peptide β (1−40)

Recent studies have shown that at physiological conditions (pH 7.6, 37 °C), the reactivity of recombinant apoE isoforms secreted by mammalian cells toward amyloid peptide β (Aβ40) follows the order apoE2 > apoE3 > apoE4 for the apoE monomer and apoE2 > apoE3 for apoE dimer that is formed vi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Easton) 1999-07, Vol.38 (28), p.8918-8925
Hauptverfasser:	Aleshkov, Sergei B, Li, Xiaoping, Lavrentiadou, Sophia N, Zannis, Vassilis I
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!