New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain

New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biochemistry (Easton) 1997-10, Vol.36 (43), p.13180-13186
Hauptverfasser: Lee, Sheng-Lian, Alexander, Richard S., Smallwood, Angela, Trievel, Raymond, Mersinger, Lawrence, Weber, Patricia C., Kettner, Charles
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 13186
container_issue 43
container_start_page 13180
container_title Biochemistry (Easton)
container_volume 36
creator Lee, Sheng-Lian
Alexander, Richard S.
Smallwood, Angela
Trievel, Raymond
Mersinger, Lawrence
Weber, Patricia C.
Kettner, Charles
description
doi_str_mv 10.1021/bi970912m
format Article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1021_bi970912m</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1021_bi970912m</sourcerecordid><originalsourceid>FETCH-LOGICAL-c159t-b207e2d8f7a588e644db84ede250da991da025cf3a187e8fccbda79a0427d0ed3</originalsourceid><addsrcrecordid>eNo90EtOwzAQBmALgUR5LLjBbFkEbDdpYnZtxUuqaEXLOprEE2La2JUdhLpjy604CychURGr0Yz0fyP9jF0IfiW4FNeFUSlXQjYHbCASyaNYqeSQDTjno0iqET9mJyG8dWvM03jAvp_oAx5tbQrTOh_AVbCqvWsKYwGthnlbk4eV322DsdHGrAkW3rWEgcLNz-cXPOy0d69kYeKsNva1F9DCuDOwNSVMd2gd3Hv3voUP09aAMMFyXThLMG6Mpj7QPYEFCJiYvbE0LcEzbTdYUvi_9nIXDp267IPTGo09Y0cVbgKd_81T9nJ3u5o-RLP5_eN0PItKkag2KiRPSeqsSjHJMhrFsS6ymDTJhGtUSmjkMimrIYospawqy0JjqpDHMtWc9PCUXe7d0rsQPFX51psG_S4XPO-rz_-rH_4C4Qx5uA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain</title><source>ACS Publications</source><creator>Lee, Sheng-Lian ; Alexander, Richard S. ; Smallwood, Angela ; Trievel, Raymond ; Mersinger, Lawrence ; Weber, Patricia C. ; Kettner, Charles</creator><creatorcontrib>Lee, Sheng-Lian ; Alexander, Richard S. ; Smallwood, Angela ; Trievel, Raymond ; Mersinger, Lawrence ; Weber, Patricia C. ; Kettner, Charles</creatorcontrib><identifier>ISSN: 0006-2960</identifier><identifier>EISSN: 1520-4995</identifier><identifier>DOI: 10.1021/bi970912m</identifier><language>eng</language><ispartof>Biochemistry (Easton), 1997-10, Vol.36 (43), p.13180-13186</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c159t-b207e2d8f7a588e644db84ede250da991da025cf3a187e8fccbda79a0427d0ed3</citedby><cites>FETCH-LOGICAL-c159t-b207e2d8f7a588e644db84ede250da991da025cf3a187e8fccbda79a0427d0ed3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2752,27901,27902</link.rule.ids></links><search><creatorcontrib>Lee, Sheng-Lian</creatorcontrib><creatorcontrib>Alexander, Richard S.</creatorcontrib><creatorcontrib>Smallwood, Angela</creatorcontrib><creatorcontrib>Trievel, Raymond</creatorcontrib><creatorcontrib>Mersinger, Lawrence</creatorcontrib><creatorcontrib>Weber, Patricia C.</creatorcontrib><creatorcontrib>Kettner, Charles</creatorcontrib><title>New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain</title><title>Biochemistry (Easton)</title><issn>0006-2960</issn><issn>1520-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNo90EtOwzAQBmALgUR5LLjBbFkEbDdpYnZtxUuqaEXLOprEE2La2JUdhLpjy604CychURGr0Yz0fyP9jF0IfiW4FNeFUSlXQjYHbCASyaNYqeSQDTjno0iqET9mJyG8dWvM03jAvp_oAx5tbQrTOh_AVbCqvWsKYwGthnlbk4eV322DsdHGrAkW3rWEgcLNz-cXPOy0d69kYeKsNva1F9DCuDOwNSVMd2gd3Hv3voUP09aAMMFyXThLMG6Mpj7QPYEFCJiYvbE0LcEzbTdYUvi_9nIXDp267IPTGo09Y0cVbgKd_81T9nJ3u5o-RLP5_eN0PItKkag2KiRPSeqsSjHJMhrFsS6ymDTJhGtUSmjkMimrIYospawqy0JjqpDHMtWc9PCUXe7d0rsQPFX51psG_S4XPO-rz_-rH_4C4Qx5uA</recordid><startdate>19971028</startdate><enddate>19971028</enddate><creator>Lee, Sheng-Lian</creator><creator>Alexander, Richard S.</creator><creator>Smallwood, Angela</creator><creator>Trievel, Raymond</creator><creator>Mersinger, Lawrence</creator><creator>Weber, Patricia C.</creator><creator>Kettner, Charles</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19971028</creationdate><title>New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain</title><author>Lee, Sheng-Lian ; Alexander, Richard S. ; Smallwood, Angela ; Trievel, Raymond ; Mersinger, Lawrence ; Weber, Patricia C. ; Kettner, Charles</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c159t-b207e2d8f7a588e644db84ede250da991da025cf3a187e8fccbda79a0427d0ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Sheng-Lian</creatorcontrib><creatorcontrib>Alexander, Richard S.</creatorcontrib><creatorcontrib>Smallwood, Angela</creatorcontrib><creatorcontrib>Trievel, Raymond</creatorcontrib><creatorcontrib>Mersinger, Lawrence</creatorcontrib><creatorcontrib>Weber, Patricia C.</creatorcontrib><creatorcontrib>Kettner, Charles</creatorcontrib><collection>CrossRef</collection><jtitle>Biochemistry (Easton)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Sheng-Lian</au><au>Alexander, Richard S.</au><au>Smallwood, Angela</au><au>Trievel, Raymond</au><au>Mersinger, Lawrence</au><au>Weber, Patricia C.</au><au>Kettner, Charles</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain</atitle><jtitle>Biochemistry (Easton)</jtitle><date>1997-10-28</date><risdate>1997</risdate><volume>36</volume><issue>43</issue><spage>13180</spage><epage>13186</epage><pages>13180-13186</pages><issn>0006-2960</issn><eissn>1520-4995</eissn><doi>10.1021/bi970912m</doi><tpages>7</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0006-2960
ispartof Biochemistry (Easton), 1997-10, Vol.36 (43), p.13180-13186
issn 0006-2960
1520-4995
language eng
recordid cdi_crossref_primary_10_1021_bi970912m
source ACS Publications
title New Inhibitors of Thrombin and Other Trypsin-like Proteases:  Hydrogen Bonding of an Aromatic Cyano Group with a Backbone Amide of the P 1 Binding Site Replaces Binding of a Basic Side Chain
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T17%3A33%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=New%20Inhibitors%20of%20Thrombin%20and%20Other%20Trypsin-like%20Proteases:%E2%80%89%20Hydrogen%20Bonding%20of%20an%20Aromatic%20Cyano%20Group%20with%20a%20Backbone%20Amide%20of%20the%20P%201%20Binding%20Site%20Replaces%20Binding%20of%20a%20Basic%20Side%20Chain&rft.jtitle=Biochemistry%20(Easton)&rft.au=Lee,%20Sheng-Lian&rft.date=1997-10-28&rft.volume=36&rft.issue=43&rft.spage=13180&rft.epage=13186&rft.pages=13180-13186&rft.issn=0006-2960&rft.eissn=1520-4995&rft_id=info:doi/10.1021/bi970912m&rft_dat=%3Ccrossref%3E10_1021_bi970912m%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true