Structural Basis for Dimerization of the BNIP3 Transmembrane Domain

Mutagenesis data suggest that BNIP3 transmembrane domain dimerization depends critically on hydrogen bonding between His 173 and Ser 172, but a recent structural analysis indicates that these residues adopt multiple conformations and are not always hydrogen bonded. We show that in dodecylphosphochol...

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Veröffentlicht in:	Biochemistry (Easton) 2009-06, Vol.48 (23), p.5106-5120
Hauptverfasser:	Sulistijo, Endah S, MacKenzie, Kevin R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Hydrogen Bonding Hydrophobic and Hydrophilic Interactions Membrane Proteins - chemistry Membrane Proteins - metabolism Models, Molecular Molecular Sequence Data Peptides - chemistry Peptides - metabolism Protein Conformation Protein Folding Protein Multimerization Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism
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