Stability, Homodimerization, and Calcium-Binding Properties of a Single, Variant βγ-Crystallin Domain of the Protein Absent in Melanoma 1 (AIM1)

AIM1 (absent in melanoma), a candidate suppressor of malignancy in melanoma, is a nonlens member of the βγ-crystallin superfamily, which contains six predicted βγ domains. The first βγ-crystallin domain of AIM1 (AIM1-g1) diverges most in sequence from the superfamily consensus. To examine its abilit...

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Veröffentlicht in:Biochemistry (Easton) 2003-04, Vol.42 (15), p.4552-4559
Hauptverfasser: Rajini, Bheemreddy, Graham, Caroline, Wistow, Graeme, Sharma, Yogendra
Format: Artikel
Sprache:eng
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