Dominant Thermodynamic Role of the Third Independent Receptor Binding Site in the Receptor-Associated Protein RAP

The 39 kDa receptor-associated protein (RAP) is a three-domain escort protein in the secretory pathway for several members of the low-density lipoprotein receptor (LDLR) family of endocytic receptors, including the LDLR-related protein (LRP). The minimal functional unit of LRP required for efficient...

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Veröffentlicht in:	Biochemistry (Easton) 2001-12, Vol.40 (50), p.15408-15417
Hauptverfasser:	Andersen, Olav M, Schwarz, Frederick P, Eisenstein, Edward, Jacobsen, Christian, Moestrup, Søren K, Etzerodt, Michael, Thøgersen, Hans C
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Humans In Vitro Techniques LDL-Receptor Related Protein-Associated Protein - chemistry LDL-Receptor Related Protein-Associated Protein - genetics LDL-Receptor Related Protein-Associated Protein - metabolism Ligands Macromolecular Substances Mutagenesis, Site-Directed Protein Conformation Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism Surface Plasmon Resonance Thermodynamics
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