Isolation and Characterization of EMS16, a C-Lectin Type Protein from Echis multisquamatus Venom, a Potent and Selective Inhibitor of the α2β1 Integrin

We have isolated and characterized EMS16, a potent and selective inhibitor of the α2β1 integrin, from Echis multisquamatus venom. It belongs to the family of C-lectin type of proteins (CLPs), and its amino acid sequence is homologous with other members of this protein family occurring in snake venom...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Easton) 2000-08, Vol.39 (32), p.9859-9867
Hauptverfasser:	Marcinkiewicz, Cezary, Lobb, Roy R, Marcinkiewicz, Mariola M, Daniel, James L, Smith, J. Bryan, Dangelmaier, Carol, Weinreb, Paul H, Beacham, Dorothy A, Niewiarowski, Stefan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!