Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties

Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties

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Veröffentlicht in:Biochemistry (Easton) 1995-08, Vol.34 (30), p.9670-9676
Hauptverfasser: Trzaskos, James M, Ko, Soo S, Magolda, Ronald L, Favata, Margaret F, Fischer, Robert T, Stam, Simon H, Johnson, Paul R, Gaylor, James L
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container_end_page 9676
container_issue 30
container_start_page 9670
container_title Biochemistry (Easton)
container_volume 34
creator Trzaskos, James M
Ko, Soo S
Magolda, Ronald L
Favata, Margaret F
Fischer, Robert T
Stam, Simon H
Johnson, Paul R
Gaylor, James L
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doi_str_mv 10.1021/bi00030a003
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title Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties
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