Carrier Design:  New Generation of Polycationic Branched Polypeptides Containing OH Groups with Prolonged Blood Survival and Diminished in Vitro Cytotoxicity

For the construction of macromolecule−drug conjugates, it is important to provide rational basis to the selection of proper carrier. With respect to the importance of the side-chain structure and charge of the branched polypeptides in biological properties, we have prepared a new class of branched p...

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Veröffentlicht in:Bioconjugate chemistry 1999-09, Vol.10 (5), p.781-790
Hauptverfasser: Hudecz, Ferenc, Pimm, Malcolm V, Rajnavölgyi, Éva, Mezo, G´bor, Fabra, Angels, Gaál, Dezső, Kovács, Attila L, Horváth, Attila, Szekerke, Mária
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Sprache:eng
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