Palladium-Catalyzed α-Arylation of Cyclic β-Dicarbonyl Compounds for the Synthesis of Ca V 1.3 Inhibitors

Cyclic α-aryl β-dicarbonyl derivatives are important scaffolds in medicinal chemistry. Palladium-catalyzed coupling reactions of haloarenes were conducted with diverse five- to seven-membered cyclic β-dicarbonyl derivatives including barbiturate, pyrazolidine-3,5-dione, and 1,4-diazepane-5,7-dione....

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Veröffentlicht in:	ACS omega 2022-04, Vol.7 (16), p.14252-14263
Hauptverfasser:	Yun, Jisu, Jeong, Dayeon, Xie, Zhong, Lee, Sol, Kim, Jiho, Surmeier, D James, Silverman, Richard B, Kang, Soosung
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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