Oncolytic Adenovirus Complexes Coated with Lipids and Calcium Phosphate for Cancer Gene Therapy

Oncolytic adenovirus (OncoAd) is a promising therapeutic agent for treating cancer. However, the therapeutic potential of OncoAd is hindered by hepatic sequestration and the host immune response in vivo. Here, we constructed a PEG/Lipids/calcium phosphate (CaP)-OncoAd (PLC-OncoAd) delivery system fo...

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Veröffentlicht in:ACS nano 2016-12, Vol.10 (12), p.11548-11560
Hauptverfasser: Chen, Jianhua, Gao, Pei, Yuan, Sujing, Li, Rongxin, Ni, Aimin, Chu, Liang, Ding, Li, Sun, Ying, Liu, Xin-Yuan, Duan, Yourong
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Sprache:eng
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