Screening and Evaluation of Flavonoids as Xanthine Oxidase Inhibitors for Reducing Uric Acid through Combined Cell Biology and Molecular Simulation

Xanthine oxidase (XO) is an important target for the treatment of hyperuricemia (HUA), which mediates the production of uric acid (UA). The mechanism of action between flavonoids and XO in cell biology and structural bioinformatics has not been fully explored. In this study, 160 flavonoids were exte...

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Veröffentlicht in:	ACS food science & technology 2021-12, Vol.1 (11), p.2182-2191
Hauptverfasser:	Wang, Yifan, Zhang, Siyu, Zhang, Yidan, Yao, Fengli, Zhao, Guangjian, Wang, Juan, Liu, Lu, Yang, Yacong, Li, Xionghao, Sun, Yujie, Hu, Yu, Bai, Zhongyue, Wang, Peng, Li, Rong, Xu, Ximing
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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