Impact of Gold Nanoparticles on Amyloid β‑Induced Alzheimer’s Disease in a Rat Animal Model: Involvement of STIM Proteins

Alzheimer’s disease (AD) is the most common type of neurodegenerative amyloid disorder causing progressive cognitive decline and memory loss. A considerable number of therapies for AD rely on inhibition/delay/dissociation of amyloid beta (Aβ) oligomers and fibrils. In this case, nanoparticles (NPs)...

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Veröffentlicht in:	ACS chemical neuroscience 2019-05, Vol.10 (5), p.2299-2309
Hauptverfasser:	Sanati, Mehdi, Khodagholi, Fariba, Aminyavari, Samaneh, Ghasemi, Forough, Gholami, Mahdi, Kebriaeezadeh, Abbas, Sabzevari, Omid, Hajipour, Mohammad Javad, Imani, Mohammad, Mahmoudi, Morteza, Sharifzadeh, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - metabolism Alzheimer Disease - pathology Amyloid beta-Peptides - metabolism Animals Cyclic AMP Response Element-Binding Protein - metabolism Disease Models, Animal Gold Hippocampus - drug effects Hippocampus - metabolism Hippocampus - pathology Male Maze Learning - drug effects Memory - drug effects Metal Nanoparticles - administration & dosage Metal Nanoparticles - therapeutic use Mice Phosphorylation - drug effects Rats Rats, Wistar Stromal Interaction Molecule 1 - metabolism Stromal Interaction Molecule 2 - metabolism
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