In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix

The extracellular matrix (ECM) contributes to tumor progression through changes induced by tumor and stromal cell signals that promote increased ECM density and stiffness. The increase in ECM stiffness is known to promote tumor cell invasion into surrounding tissues and metastasis. In addition, this...

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Veröffentlicht in:ACS chemical biology 2018-10, Vol.13 (10), p.2825-2840
Hauptverfasser: Fleming, Jodie M, Yeyeodu, Susan T, McLaughlin, Ashley, Schuman, Darren, Taylor, Darlene K
Format: Artikel
Sprache:eng
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