Phospholipids Differentially Regulate Ca 2+ Binding to Synaptotagmin-1

Synaptotagmin-1 (Syt-1) is a calcium sensing protein that is resident in synaptic vesicles. It is well established that Syt-1 is essential for fast and synchronous neurotransmitter release. However, the role of Ca and phospholipid binding in the function of Syt-1, and ultimately in neurotransmitter...

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Veröffentlicht in:	ACS chemical biology 2024-04, Vol.19 (4), p.953-961
Hauptverfasser:	Lawrence, Sophie A S, Kirschbaum, Carla, Bennett, Jack L, Lutomski, Corinne A, El-Baba, Tarick J, Robinson, Carol V
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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