Efficient O‑Glycosylation of Triterpenes Enabled by Protein Engineering of Plant Glycosyltransferase UGT74AC1

Triterpene O-glycosylation has attracted significant interest from the pharmaceutical industry as a valuable means for drug design and development. Plant glycosyltransferases, which catalyze this glycosylation reaction, play a key step in preparing structure diverse and valuable triterpene glycoside...

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Veröffentlicht in:ACS catalysis 2020-03, Vol.10 (6), p.3629-3639
Hauptverfasser: Li, Jiao, Yang, Jiangang, Mu, Shicheng, Shang, Na, Liu, Cui, Zhu, Yueming, Cai, Yi, Liu, Pi, Lin, Jianping, Liu, Weidong, Sun, Yuanxia, Ma, Yanhe
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Sprache:eng
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