Methoxamine Synthesis in a Biocatalytic 1‑Pot 2‑Step Cascade Approach

Due to its function as a vasopressor, the vicinal amino alcohol methoxamine is a potential candidate for the treatment of hypotension and incontinence or has applications in ophthalmology. In this study, a biocatalytic method was developed to produce each of the four stereoisomers of methoxamine in...

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Veröffentlicht in:	ACS catalysis 2019-08, Vol.9 (8), p.7380-7388
Hauptverfasser:	Erdmann, Vanessa, Sehl, Torsten, Frindi-Wosch, Ilona, Simon, Robert C, Kroutil, Wolfgang, Rother, Dörte
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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