Crotonases: Nature’s Exceedingly Convertible Catalysts

The crotonases comprise a widely distributed enzyme superfamily that has multiple roles in both primary and secondary metabolism. Many crotonases employ oxyanion hole-mediated stabilization of intermediates to catalyze the reaction of coenzyme A (CoA) thioester substrates (e.g., malonyl-CoA, α,β-uns...

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Veröffentlicht in:	ACS catalysis 2017-10, Vol.7 (10), p.6587-6599
Hauptverfasser:	Lohans, Christopher T, Wang, David Y, Wang, Jimmy, Hamed, Refaat B, Schofield, Christopher J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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