Merging Chemo- and Biocatalysis to Facilitate the Syntheses of Complex Natural Products: Enantioselective Construction of an N‑Bridged [3.3.1] Ring System in Indole Terpenoids

Although the molecular structural motif of indole-fused azabicyclo[3.3.1]­nonane is common in biologically significant natural products, its catalytic asymmetric synthesis remains underexplored. Herein, we report a catalytic approach for the formal synthesis of more than 20 types of sarpagine/macrol...

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Veröffentlicht in:	ACS catalysis 2022-12, Vol.12 (24), p.14990-14998
Hauptverfasser:	Hashimoto, Yoshinori, Harada, Shingo, Kato, Ryosuke, Ikeda, Kotaro, Nonnhoff, Jannis, Gröger, Harald, Nemoto, Tetsuhiro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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