Pd II -Catalyzed γ -C(sp 3 )-H (Hetero)Arylation of Ketones Enabled by Transient Directing Groups

Pd(II)-catalyzed -C(sp )-H (hetero)arylation of aliphatic ketones is developed using -amino acid as transient directing groups (TDG). A variety of aliphatic ketones were (hetero)arylated at the -position via a 5,6-membered fused cyclopalladation intermediate to afford the remotely arylated products...

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Veröffentlicht in:	ACS catalysis 2022-09, Vol.12 (17), p.10581-10586
Hauptverfasser:	Li, Yi-Hao, Ouyang, Yuxin, Chekshin, Nikita, Yu, Jin-Quan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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