Access to Enantioenriched 1,n‑Diamines via Ni-Catalyzed Hydroamination of Unactivated Alkenes with Weakly Coordinating Groups

Enantioenriched 1,2- and 1,3-diamines with chiral α-branched aliphatic amine motifs are important substructures in bioactive compounds and related molecules and serve as privileged chiral ligands in both organo- and transition-metal-catalysis. However, direct access to such structural motifs remains...

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Veröffentlicht in:ACS catalysis 2022-08, Vol.12 (15), p.9638-9645
Hauptverfasser: Yang, Peng-Fei, Liang, Jian-Xing, Zhao, Han-Tong, Shu, Wei
Format: Artikel
Sprache:eng
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